Abstract: Introduction: The latest nationwide survey on Behcet’s disease (BD) in Iran was carried out in 2001. We present here its data, and compare it with the previous two surveys in 1991 (on 1882 patients) and 1996 (on 3153 patients). Patients & methods: The data of patients in the BD registry before the end of the year 2001 were collected on a standard protocol comprising 100 clinical and paraclinical items. A ...
Abstract: Background: The gene effect in pathogenesis of Rheumatic Diseases is well known, but the exact mode of transmission is not clear. In this report we present similar diseases occurred in two generations and in siblings. Methods: We overviewed the medical charts of second member of the family, according to the family history of the index patient. Results: Family I: Discoid Lupus was diagnosed in an eight years old girl whose father had ...
Abstract: Introduction: Behcet's disease (BD) is underdiagnosed in children. It is mainly due to the wide range manifestations of the disease, the low specificity of the symptoms, and the unfamiliarity of most physicians with childhood BD. These patients are not included in the juvenile group and may be a cause of controversy in the description of BD in children. The aim of this study was to find if the characteristics of ...
Abstract: Introduction: Different methods of treatment were employed in ocular lesions of Behcet’s disease (BD) in adults. Most of them are not permitted in children due to their potential toxicity. Methotrexate (MTX) has gained wide acceptance for the treatment of childhood rheumatic diseases. On the other hand, we showed in several reports the efficacy of MTX in the treatment of ocular lesions of BD. This study was designed to show the ...
Abstract: Aim: The aim of this study was to assess the demography of polymyositis in Iranian children. Methods: 47 children classified by the ACR Criteria as having polymyositis were studied. 95 items were checked for every patient. They were followed regularly and the data were updated at each visit. Results: Thirty patients were female (64%). The acute presentation of the disease was seen in 10%. The manifestations at the onset of ...
Abstract: Scleroderma may occur in childhood with different characteristics. The present study shows the picture of scleroderma in Iranian children and compares the characteristics in children and adults. Methods: 56 scleroderma patients under 16 were compared with 217 adult scleroderma seen since 1975. Data were compared with Chi square test. Results: Girls were 44 (79%) and boys 12. The initial presentation was: Raynaud's phenomenon 68%, skin edema 27%, limb skin sclerosis 66%, ...
Abstract: Introduction: There is considerable controversy in the characteristics of Behect's disease (BD) in children. The aim of this study is to show Iran's view m juvenile BD. Materials & Methods: Different manifestations of the disease were determined in the BD patients under the age of 16. They were compared with the adult patients by chi square test. Results: We had 102 children with BD. The male/female ratio was 1.04. Oral aphthosis (64%) ...
Abstract: Systemic Lupus Erythematosus is not rare in Iran. We have seen 220 cases in children in a population of 893 SLE in the past 16 years. In this study we show the features of SLE in children. The female to male ratio was 86/14. Fever was present in 72% of the patients, weight loss in 40%, malar rash in 72.5%, photosensitivity in 54%, mucosal lesion in 48%, discoid rash in ...
Abstract: An increased rate of infection among SLE patients has long been reported from western countries. In a retrospective study in 893 patients, we analyzed 203 cases who had one or more episodes of infection between 1974 and 1992. Among them 181 were females and 22 were males (89% female) . The diagnosis of infection was established by both clinical and laboratory findings. Almost more than half of the infections were ...